Frontline Combo Puppy (2-10 kg) with Fipronil to protect pups (8 weeks and older, 2 kg and up) against fleas, ticks and lice. Frontline Combo pup contains a single dropper to protect your dog for up to 8 weeks against fleas and up to 4 weeks against ticks. Fleas already present on the animal are killed within 24 hours and it also offers protection against new fleas. The complete dropper can be used in the neck, or at least a place that is hard to reach for the animal itself or a roommate until it is dry.